Pattern Recognition in Computational Molecular Biology. Techniques and Approaches

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Content-Based Retrieval of Microarray Experiments.

New Books in the Biomedical Libraries – November 2016

N2 - This chapter introduces the basic terminology and techniques in conventional information retrieval systems. AB - This chapter introduces the basic terminology and techniques in conventional information retrieval systems. Parmak izi Content based retrieval. Information retrieval. Information retrieval systems. Gene expression.

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Bioinformatics part 2 Databases (protein and nucleotide)

No notes for slide. Pattern recognition techniques for the emerging feilds in bioinformatics 1. Atukorale Dec 1 2. With the wealth of sequence data in many public online databases and the huge amount of data generated from the Human Genome Project, computer analysis has become indispensable. This calls for novel algorithms and opens up new areas of applications for many pattern recognition tech- niques.

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Iterated Local Search for Biclustering of Microarray Data | SpringerLink

This paper describe current methods, tools, algorithms and show how pattern recognition techniques could be useful in these areas. It is my hope that this review article could demonstrate how the pattern recognition community could have an impact on the fascinating and challenging area of genomic research.

Contents 1 Introduction 7 1. List of Figures 1 The composition of Pattern Recognition system. The numerous biological data are diagnosed earlier and to do matching successfully the computational method was essential. For this, the pattern recognition technology and the techniques relevant to this were the most successful remedy. It involves the development and advancement of algorithms using techniques including pattern recognition, machine learning, applied mathematics, statistics, informat- ics, and biology to solve biological problems usually on the molecular level.

Bioinformatics also can be described as development and application of computational method to make biological discoveries[1]. Pattern recognition methods are built on the assumption that some underlying charac- teristics of protein sequence or of a protein structure, can be used to identify similar traits in related proteins. In other words, if part of a sequence or structure is preserved or conserved this characteristic may be used to diagnose new family members.

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If such conserved traits are distilled from known protein families and stored in databases, then newly sequenced proteins may be rapidly analyze to determine whether they contain these previously recognized fam- ily characteristics. Searches of sequence pattern databases, and of fold template databases, are now routinely used to diagnose family relationships and hence to infer structure and functions of newly determined sequences[3].

Under each topic this article discuss the novel techniques and tools which are existing now. The task of pattern recognition is encountered in a wide range of human activity. In a broader perspective, the term could cover any context in which some decision or forecast is made on the basis of currently available information.

Mathematically, the problem of pattern recognition deals with the construction of a procedure to be applied to a set of inputs; the procedure assigns each new input to one of a set of classes on the basis of observed features. It is a classical method and it is based on feature vector distributing which getting from probability and statistical model. In statistical pattern recognition deals with features only without consider the relations between features[4].

In general, the method of data clustering can be partitioned two classes, one is hierarchical clustering, and the other is partition clustering. The neural approach applies biological concept to machines to recognize pat- tern. In addition, genetic algorithms applied in neural networks is a statistical optimized algorithms proposed by Holland Structural pattern recognition emphases on the description of the structure, namely explain how some simple sub patterns compose one pattern.

There are two main method in structural pattern recognition, structure matching and syntax analysis.

Protein fold recognition using the gradient boost algorithm.

The basic of structure matching is some special technique of mathematics based on sub-pattern. Whether the decision made by the system right or not mainly depending on the decision make by the human expert. Data building convert original infor- mation into vector which can be dealt with by computer. Figure 1: The composition of Pattern Recognition system 11 And also newly introduced pattern recognition techniques are widely using under this topic.

Figure 2: Co protein complex with DNA 3. Currently both computational and experimental techniques have been developed to identify the protein-DNA interactions.


  • Random marginal agreement coefficients: rethinking the adjustment for chance when measuring agreem.
  • Content-Based Retrieval of Microarray Experiments?
  • Protein fold recognition using the gradient boost algorithm.?
  • Introduction To Interval Analysis;
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